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Welcome to the Southeastern Fertility Center's Home Page

The Southeastern Center for Fertility and Reproductive Surgery offers this site as an information resource for couples coping with the difficulties of infertility. Just as our center provides the most advanced treatment for our patients, this site provides the most recent and accurate medical information concerning infertility and reproductive surgery.

Located in Knoxville, Tennessee, the center specializes in the diagnosis and treatment of male and female infertility problems. Under the direction of Jeffrey A. Keenan MD, HCLD, our patients receive the highest quality medical care available in the region. Dr. Keenan is one of the most experienced and respected specialists in infertility and reproductive medicine and surgery.

We provide updates on this site to ensure you are receiving the latest information. If you wish to schedule an appointment with us or have questions, please call us at (865) 777-0088 or click here to use our appointment request form.

Dr. Jeffrey A. Keenan

Spring-Summer Update 2017

It has certainly been a wet spring and is looking to be a hot summer. We've been blessed with many positive pregnancy tests as of late. Have you been trying for pregnancy but have been unsuccessful? If so, call today to schedule an appointment. We can help to get you on track towards the family you've always dreamed of. We also offer general GYN services, so if you need to do a little "spring cleaning" of your healthcare, call today to schedule an appointment.

Welcome Back!

Please join us in welcoming our nurse practitioner, Autumn Galbraith, back from maternity leave. She welcomed a beautiful baby boy, Silas James, in February (see pictures below). She loves being a new mommy, and has now resumed seeing patients. Call today to schedule an appointment with her. Also, a big thanks to nurse practitioner, Sarah Alexander, for filling in for Autumn while she was out.

Spring-Summer Observances

  • April is STI Awareness Month
  • April 23rd: 29th is National Infertility Awareness Week
  • May is National Osteoporosis Awareness and Prevention Month
  • May is National Preeclampsia Awareness Month
  • May 14th: 20th is National Alcohol and Other Drug-Related Birth Defects Week
  • May 14th: 20th is National Women's Health Week
  • August is National Breastfeeding Month
  • August 1st-7th is World Breastfeeding Week

Literature Review

Have PCOS and Difficulty Losing Weight?

There may be an answer as to why it is more difficult for women with polycystic ovarian syndrome (PCOS) to lose weight. Basic metabolic rate (BMR) is the energy expenditure of a person at rest. It represents 50%-70% of total daily energy expenditure. A study of 91 women with PCOS compared with 48 women without PCOS revealed that the PCOS women had significantly lower BMRs. A low BMR might be a predisposing factor for obesity and increased insulin resistance in women with PCOS. So, what's the bottom line? As a woman with PCOS, you will probably have to put in significantly more effort towards diet and exercise as your non-PCOS counterparts. So unfair! But, knowledge is power, and now you know!

Postmenopausal Estrogen and Cardiovascular Disease

Previous data have suggested that estrogen-containing hormone therapy is associated with beneficial effects with regard to cardiovascular disease when the therapy is initiated shortly after the onset of menopause. In a recent study, 643 postmenopausal women were divided into two groups, early postmenopausal (10 years since menopause). After a median of 5 years, the effect of estradiol, with or without progesterone, on carotid-artery intima media thickness (CIMT) (a measure of subclinical atherosclerosis) differed between the early and late postmenopausal groups. Oral estradiol therapy was associated with less progression of subclinical atherosclerosis (measured as CIMT) than was placebo when therapy was initiated within 6 years after menopause, but not when it was initiated 10 or more years after menopause. CT measures of coronary-artery calcium, total stenosis, and plaque did no differ significantly between either groups. Why is this important? If you are, or when you become, menopausal, this information is important for the decision of whether or not to begin/continue hormone replacement therapy (HRT). And HRT can have a significant positive (or negative) impact on your health and longevity. The story is complicated, so see us or your OB/GYN to discuss this topic when you enter that stage of life!

Does Sperm Contribute to Recurrent Pregnancy Loss (RPL)?

A study published in Fertility and Sterility compared semen samples from 26 male partners of women with RPL and 31 males with normal sperm with proven fertility. Mean DNA fragmentation was significantly more in men with RPL, thus, sperm DNA fragmentation may play a role in unexplained RPL despite normal semen analysis parameters.